Lucienne joined PwC Malta in 1997 after graduating in Accountancy from the University of Malta. She is a Certified Public Accountant (CPA) and a member of the Association of Chartered Certified Accountants (FCCA) and the Malta Institute of Accountants (MIA), where she currently serves as vice-president. 

She was appointed Assurance partner at PwC on 1 July 2006 and assumed the role of quality and risk management partner in 2011. Lucienne has acted as assurance engagement leader on a diverse client portfolio, including groups of companies and other non-group companies that vary in size and structure. Her experience spans the audit of local and foreign-owned companies across multiple industries and sectors. She has complemented her experience with secondments to PwC offices in New York and Brussels and has participated in and led various global projects at a network level. 

Lucienne was elected Territory Senior Partner of the firm on 1 October 2025.